KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATM
All Species:
17.58
Human Site:
T2194
Identified Species:
42.96
UniProt:
Q13315
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13315
NP_000042.3
3056
350687
T2194
E
L
F
S
R
S
V
T
H
R
Q
L
S
E
V
Chimpanzee
Pan troglodytes
XP_001139487
3056
350692
T2194
E
L
F
S
R
S
V
T
H
R
Q
L
S
E
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62388
3066
349469
T2203
E
L
F
S
R
S
V
T
D
R
E
R
S
E
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001155872
3050
347768
T2188
L
L
F
S
R
P
A
T
T
Q
Q
L
N
D
I
Frog
Xenopus laevis
Q9DE14
2654
301441
K1879
C
E
L
E
H
S
V
K
M
F
L
Q
K
P
S
Zebra Danio
Brachydanio rerio
XP_002667249
1913
215524
T1138
T
P
T
S
R
P
T
T
P
M
L
S
D
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q5EAK6
2767
317973
P1992
S
E
F
Y
Q
K
D
P
I
S
T
Y
L
M
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107666
3120
349933
T2251
P
F
I
L
R
H
R
T
D
S
L
P
I
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M3G7
3856
435096
S3005
D
L
R
W
T
T
S
S
H
Q
S
V
H
G
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RZT9
2939
328678
S2129
D
D
V
S
R
I
L
S
C
R
E
T
T
L
S
Conservation
Percent
Protein Identity:
100
99.4
N.A.
N.A.
N.A.
83.8
N.A.
N.A.
N.A.
69.5
20.5
35.1
N.A.
22.1
N.A.
N.A.
36.2
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
91.3
N.A.
N.A.
N.A.
82.8
39.9
46.3
N.A.
42.8
N.A.
N.A.
56.7
P-Site Identity:
100
100
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
46.6
13.3
20
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
80
N.A.
N.A.
N.A.
73.3
13.3
20
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
N.A.
20.8
Protein Similarity:
N.A.
N.A.
N.A.
42.5
N.A.
40.9
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% A
% Cys:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
20
10
0
0
0
0
10
0
20
0
0
0
10
10
10
% D
% Glu:
30
20
0
10
0
0
0
0
0
0
20
0
0
30
0
% E
% Phe:
0
10
50
0
0
0
0
0
0
10
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% G
% His:
0
0
0
0
10
10
0
0
30
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
10
0
0
0
10
0
10
% I
% Lys:
0
0
0
0
0
10
0
10
0
0
0
0
10
0
10
% K
% Leu:
10
50
10
10
0
0
10
0
0
0
30
30
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
10
10
0
0
0
20
0
10
10
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
20
30
10
0
0
0
% Q
% Arg:
0
0
10
0
70
0
10
0
0
40
0
10
0
0
0
% R
% Ser:
10
0
0
60
0
40
10
20
0
20
10
10
30
10
20
% S
% Thr:
10
0
10
0
10
10
10
60
10
0
10
10
10
0
0
% T
% Val:
0
0
10
0
0
0
40
0
0
0
0
10
0
0
20
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _